Quest for the descent of the Escherichia coli outbreak strain TY2482 – out of Germany? | Zendy

Tiruvayipati Avasthi | Zendy; Narender Kumar | Zendy; Ramani Baddam | Zendy; Singamaneni Haritha Devi | Zendy; Lothar H. Wieler | Zendy; Niyaz Ahmed | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Quest for the descent of the Escherichia coli outbreak strain TY2482 – out of Germany?

Author(s) -

Tiruvayipati Avasthi,

Narender Kumar,

Ramani Baddam,

Singamaneni Haritha Devi,

Lothar H. Wieler,

Niyaz Ahmed

Publication year - 2011

Publication title -

nature precedings

Language(s) - English

Resource type - Journals

ISSN - 1756-0357

DOI - 10.1038/npre.2011.6034.1

Subject(s) - outbreak , strain (injury) , escherichia coli , microbiology and biotechnology , german , virulence , clone (java method) , biology , whole genome sequencing , pathogenicity , virology , genome , gene , genetics , geography , archaeology , anatomy

The recent outbreak of the Escherichia coli infection in north Germany reportedly has killed 35 people and sickened about 4000. Infections were reported in 2001 and 2002 in Germany and Central Africa respectively. In order to dissect all possible connections among the three infection/outbreak strains and to extract the most virulent genes responsible for the augmented pathogenicity of the present German strain (2011), whole genome sequence data of the two isolates (E. coli TY_2482 & LB226692) were analyzed. We report that the German outbreak strain isolated in 2011 is a seasoned clone of the 2002 isolate sequenced from Central Africa (55989) and perhaps a direct descendent of the German EAEC strain reported in 2001 infection cases

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research