Dengue virus NS2B protein targets cGAS for degradation and prevents mitochondrial DNA sensing during infection
Author(s) -
Sebastián Aguirre,
Priya Luthra,
María Teresa Sánchez-Aparicio,
Ana M. Maestre,
Jenish Patel,
Francise Lamothe,
Anthony C. Fredericks,
Shashank Tripathi,
Tongtong Zhu,
Jessica Pintado-Silva,
Laurence G. Webb,
Dabeiba BernalRubio,
Alexander Solovyov,
Benjamin Greenbaum,
Viviana Simon,
Christopher F. Basler,
Lubbertus C. F. Mulder,
Adolfo Garcı́a-Sastre,
Ana FernandezSesma
Publication year - 2017
Publication title -
nature microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 7.305
H-Index - 79
ISSN - 2058-5276
DOI - 10.1038/nmicrobiol.2017.37
Subject(s) - dengue virus , interferon , dengue fever , virology , biology , innate immune system , rig i , virus , mitochondrial dna , interferon type i , antiviral protein , dna , microbiology and biotechnology , immune system , rna , gene , biochemistry , immunology
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