Open AccessReducing glutamate signaling pays off in fragile X
Author(s) -
Gary J. Bassell,
Christina Groß
Publication year - 2008
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm0308-249
Subject(s) - metabotropic glutamate receptor , fragile x syndrome , glutamate receptor , metabotropic glutamate receptor 5 , fragile x , metabotropic receptor , neuroscience , metabotropic glutamate receptor 7 , metabotropic glutamate receptor 1 , metabotropic glutamate receptor 6 , receptor , metabotropic glutamate receptor 4 , medicine , biology , bioinformatics , genetics , gene
A recent theory about the basis for fragile X syndrome is now validated in a mouse model. The findings point the way to treatment options targeting group 1 metabotropic glutamate receptors.
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