Open AccessAn epigenetic therapy for diffuse intrinsic pontine gliomas
Author(s) -
Vijay Ramaswamy,
Marc Remke,
Michael D. Taylor
Publication year - 2014
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm.3769
Subject(s) - glioma , pons , medicine , pathology , cancer research , neuroscience , biology
Diffuse intrinsic pontine glioma is a uniformly lethal malignant tumor of infancy with no effective therapies. A new study reveals that inhibition of JMJD3 has robust antitumor activity in diffuse intrinsic pontine glioma xenografts.
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