Open AccessAntiangiogenic VEGF-A in peripheral artery disease
Author(s) -
Joshua M. Boucher,
Victoria L. Bautch
Publication year - 2014
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm.3767
Subject(s) - peripheral , vascular endothelial growth factor , vegf receptors , vascular disease , medicine , arterial disease , cytokine , vascular endothelial growth factor c , vascular endothelial growth factor a , vascular endothelial growth factor b , disease , cancer research
Vascular endothelial growth factor A (VEGF-A) is a potent proangiogenic cytokine elevated in patients with peripheral artery disease (PAD). A new study links impaired vascular regrowth in PAD to increased expression of an antiangiogenic splice variant of VEGF-A.
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