Open AccessA role for interleukin-22 in the alleviation of metabolic syndrome
Author(s) -
Élise Dalmas,
Marc Y. Donath
Publication year - 2014
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm.3748
Subject(s) - glycemic , immune system , immunity , diabetes mellitus , interleukin , disease , metabolic syndrome , immunology , medicine , metabolic control analysis , interleukin 1β , endocrinology , cytokine
Increasing evidence points to a role for the immune system in the regulation of metabolism. Two new studies in mice indicate treatment with interleukin-22 restores mucosal immunity in diabetes and alleviates metabolic disease, resulting in improved glycemic control.
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