Open AccessTo B or not to B—that is the question for myocardial infarction
Author(s) -
Nancy D. Kim,
Andrew D. Luster
Publication year - 2013
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm.3367
Subject(s) - myocardial infarction , medicine , cardiology , bone marrow , chemokine , inflammation
After myocardial infarction (MI), circulating B cells produce the chemokine Ccl7, which mobilizes inflammatory monocytes from the bone marrow into the blood, after which they are then recruited to the injured heart, a new study shows. B cell depletion after MI limits myocardial injury and improves heart function, suggesting a new approach for the management of acute MI (pages 1273–1280).
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