Open AccessNKT cells—an early warning system for HBV infection
Author(s) -
Dale I. Godfrey,
Adam P. Uldrich,
Alan G. Baxter
Publication year - 2012
Publication title -
nature medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.536
H-Index - 547
eISSN - 1546-170X
pISSN - 1078-8956
DOI - 10.1038/nm.2853
Subject(s) - immune system , natural killer t cell , immunology , acquired immune system , innate immune system , hepatitis b virus , disease , biology , virology , virus , viral infection , medicine , t cell
Whereas the adaptive immune response is essential for control and clearance of hepatitis B virus infection, the importance of the early innate immune response is controversial and the players involved are poorly defined. A new study shows that activation of natural killer T cells by infected hepatocytes is crucial for the early control of this disease
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