A resource for cell line authentication, annotation and quality control | Zendy

Mamie Yu | Zendy; S. Selvaraj | Zendy; May M.Y. Liang-Chu | Zendy; Sahar Aghajani | Zendy; Matthew Busse | Zendy; Jean Yuan | Zendy; Genee Lee | Zendy; Franklin Peale | Zendy; Christiaan Klijn | Zendy; Richard Bourgon | Zendy; Joshua S. Kaminker | Zendy; Richard M. Neve | Zendy

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A resource for cell line authentication, annotation and quality control

Author(s) -

Mamie Yu,

S. Selvaraj,

May M.Y. Liang-Chu,

Sahar Aghajani,

Matthew Busse,

Jean Yuan,

Genee Lee,

Franklin Peale,

Christiaan Klijn,

Richard Bourgon,

Joshua S. Kaminker,

Richard M. Neve

Publication year - 2015

Publication title -

nature

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 15.993

H-Index - 1226

eISSN - 1476-4687

pISSN - 0028-0836

DOI - 10.1038/nature14397

Subject(s) - annotation , computer science , authentication (law) , resource (disambiguation) , computational biology , cell culture , biology , genetics , artificial intelligence , computer security , computer network

Cell line misidentification, contamination and poor annotation affect scientific reproducibility. Here we outline simple measures to detect or avoid cross-contamination, present a framework for cell line annotation linked to short tandem repeat and single nucleotide polymorphism profiles, and provide a catalogue of synonymous cell lines. This resource will enable our community to eradicate the use of misidentified lines and generate credible cell-based data.

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