Oral or intravenous iron for anemia correction in chronic kidney disease? | Zendy

Tilman B. Drüeke | Zendy; Ziad A. Massy | Zendy

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Oral or intravenous iron for anemia correction in chronic kidney disease?

Author(s) -

Tilman B. Drüeke,

Ziad A. Massy

Publication year - 2015

Publication title -

kidney international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 3.499

H-Index - 276

eISSN - 1523-1755

pISSN - 0085-2538

DOI - 10.1038/ki.2015.189

Subject(s) - intravenous iron , medicine , kidney disease , anemia , iron deficiency , hemoglobin , renal function , kidney , gastroenterology

Iron deficiency in patients with chronic kidney disease (CKD) can be corrected by the oral or intravenous route. The natural intestinal barrier against iron overload is circumvented by intravenous iron. The balance between benefit and risk of high iron doses remains unclear. In a randomized controlled trial in CKD patients, Agarwal et al. find similar effects of oral and intravenous iron on hemoglobin levels and kidney function decline but more serious cardiovascular events and infections with intravenous iron.

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