Tissue proteomics: a new investigative tool for renal biopsy analysis
Author(s) -
John R. Sedor
Publication year - 2009
Publication title -
kidney international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.499
H-Index - 276
eISSN - 1523-1755
pISSN - 0085-2538
DOI - 10.1038/ki.2009.54
Subject(s) - medicine , focal segmental glomerulosclerosis , kidney disease , biopsy , gold standard (test) , kidney , nephrology , renal pathology , pathology , renal biopsy , disease , histopathology , intensive care medicine , glomerulonephritis
Renal biopsy is viewed as the gold standard for diagnosis and management of many kidney diseases, especially glomerulopathies. However, the histopathological descriptions currently used in clinical practice often are neither diagnostic nor prognostic. The paper by Sethi et al. highlights the availability of a newer investigative tool that can be used to better define pathogenesis and, perhaps more important, to discover robust biomarkers of kidney disease cause and outcome.
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