Murine candidiasis: Strain dependence of host responses after immunization | Zendy

Ashman RB | Zendy; Papadimitriou JM | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Murine candidiasis: Strain dependence of host responses after immunization

Author(s) -

Ashman RB,

Papadimitriou JM

Publication year - 1988

Publication title -

immunology and cell biology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0818-9641

DOI - 10.1038/icb.1988.29

Subject(s) - host (biology) , immunization , strain (injury) , biology , virology , microbiology and biotechnology , immunology , genetics , immune system , anatomy

Summary After recovery from acute infection with live Candida albicans , both CBA/H and BALB/c mice show increased resistance to colonization by the organism. However, the ‘susceptible’ CBA/H mice develop much stronger protective responses than do ‘resistant’ BALB/c mice. This is manifested particularly as a substantial amelioration of the severity of the lesions in the brain, and a very marked reduction in the number of fungal units therein. Analysis of granulocyte function in normal and immune mice of the two strains tended to exclude this as a basis for the different patterns of susceptibility and resistance.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research