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Characterisation and uses of a hypervariable DNA polymorphism associated with the human J H immunoglobulin gene locus
Author(s) -
Trent RJ,
Williams BG,
Basten A
Publication year - 1987
Publication title -
immunology and cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0818-9641
DOI - 10.1038/icb.1987.42
Subject(s) - hypervariable region , locus (genetics) , genetics , gene , dna , immunoglobulin gene , polymorphism (computer science) , biology , antibody , genotype
Summary A DNA hypervariable polymorphism associated with the human immunoglobulin J H gene locus on chromosome 14 is described. Its potential applications include the distinguishing of cells as host or donor in a transplantation situation as well as characterisation of immunoglobulin gene rearrangements.