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THE INFLUENCE OF NON‐MHC GENES ON THE CYTOTOXIC T CELL RESPONSE TO MODIFIED SELF
Author(s) -
Müllbacher Arno,
Brenan Mary,
Bowern Narelle
Publication year - 1983
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1983.6
Subject(s) - cytotoxic t cell , major histocompatibility complex , biology , gene , in vitro , in vivo , virology , immunology , genetics
Summary In vivo primary cytotoxic T cell (Tc) responses to vaccinia and LCMV in H‐2 k strains and in vitro secondary responses to influenza virus in H‐2 k and H‐2 d strains appear not to be influenced by genes outside the H‐2 complex. In vitro secondary responses to Bebaru, on the other hand, are partly controlled by non‐major histocompatibility complex (MHC) genes.