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THE LOCATION OF ANTIGENIC SITES ON THE SURFACE OF THE NEMATODE PARASITE STRONGYLOIDES RATTI REACTIVE TO ANTIBODY‐DIRECTED CELLULAR CYTOTOXICITY FROM BOTH MACROPHAGES AND EOSINOPHILS FROM THE NATURAL HOST
Author(s) -
Tam ND,
Papadimitriou J,
Keast D
Publication year - 1983
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1983.59
Subject(s) - immune system , parasite hosting , biology , antigen , microbiology and biotechnology , cytotoxicity , in vitro , antibody , immunology , biochemistry , world wide web , computer science
Summary Heat‐treated and untreated sera from rats immune to Strongyloides ratti are capable of arming both immune and non‐immune macrophages and eosinophils in vitro . These cells are capable of killing larvae of the parasite. Electron microscopy has indicated multi‐point attachment of the cells to the epicuticular transverse grooves of the larvae within 4 and 24 h of incubation at 37°.