DISTRIBUTION OF THE GC (GROUP‐SPECIFIC COMPONENT) SUBTYPES IN CORD BLOODS AND BLOOD DONORS | Zendy

Nicholls Catherine | Zendy; Mulley JC | Zendy

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DISTRIBUTION OF THE GC (GROUP‐SPECIFIC COMPONENT) SUBTYPES IN CORD BLOODS AND BLOOD DONORS

Author(s) -

Nicholls Catherine,

Mulley JC

Publication year - 1982

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1982.47

Subject(s) - subtyping , isoelectric focusing , cord blood , allele , population , allele frequency , biology , microbiology and biotechnology , chemistry , genetics , gene , medicine , biochemistry , enzyme , programming language , environmental health , computer science

Summary The common allele, GC*1 , was subtyped into GC*IF and GC*IS by isoelectric focusing, increasing the proportion of heterozygotes from 0.42 to 0.58. In a series of 200 blood donors and 200 cord bloods the allele frequencies were found to be: GC*IS = 0.59, GC*IF = 0.11, GC*2 = 0.30; and GC*IS = 0.54, GC*IF = 0.16, GC*2 = 0.30, respectively. These values were similar to frequencies obtained in studies of other Caucasian populations. The average probability of detecting non‐paternity for this population is increased from 17% to 30% after subtyping GC 1.

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