Premium
DISTRIBUTION OF THE GC (GROUP‐SPECIFIC COMPONENT) SUBTYPES IN CORD BLOODS AND BLOOD DONORS
Author(s) -
Nicholls Catherine,
Mulley JC
Publication year - 1982
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1982.47
Subject(s) - subtyping , isoelectric focusing , cord blood , allele , population , allele frequency , biology , microbiology and biotechnology , chemistry , genetics , gene , medicine , biochemistry , enzyme , programming language , environmental health , computer science
Summary The common allele, GC*1 , was subtyped into GC*IF and GC*IS by isoelectric focusing, increasing the proportion of heterozygotes from 0.42 to 0.58. In a series of 200 blood donors and 200 cord bloods the allele frequencies were found to be: GC*IS = 0.59, GC*IF = 0.11, GC*2 = 0.30; and GC*IS = 0.54, GC*IF = 0.16, GC*2 = 0.30, respectively. These values were similar to frequencies obtained in studies of other Caucasian populations. The average probability of detecting non‐paternity for this population is increased from 17% to 30% after subtyping GC 1.