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IMMUNOGENICITY OF ISOLATED FOETAL MOUSE PROISLETS
Author(s) -
Simeonovic Charmaine J,
Lafferty Kevin J
Publication year - 1982
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1982.43
Subject(s) - immunogenicity , biology , transplantation , pancreas , fetus , andrology , pancreas transplantation , antigen , immunology , medicine , endocrinology , pregnancy , genetics , kidney transplantation
Summary Isolated foetal mouse proislets are significantly less immunogenic than uncultured or 10‐day cultured foetal pancreas. In contrast to uncultured and 10‐day cultured foetal pancreas allografts which are acutely rejected, a proportion of proislet allografts show no evidence of rejection up to 12 weeks post‐transplantation.