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INITIAL CHARACTERIZATION OF CRYOPRECIPITATES IN CATTLE RECOVERING FROM ACUTE BABESIA BOVIS (ARGENTINA) INFECTION
Author(s) -
Goodger BV,
Wright IG,
Mahoney DF
Publication year - 1981
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1981.45
Subject(s) - babesia bovis , antibody , fibrinogen , immune system , biology , virology , microbiology and biotechnology , immunology , babesiosis , chemistry , biochemistry
Summary The plasma of cattle recovering from severe Babesia bovis infection contained cold precipitable protein which consisted of immune complexes formed in antibody excess. The major immunoglobulin in the complexes was IgM although IgG 1 and IgG 2 were also present at lower concentrations. In addition, fibrinogen, α 2 macroglobulin and C3 component of complement were detected. As the complexes were produced after parasiteamia fell below the detectable level and the inflammatory response to B. bovis was waning, the complexes did not appear to have much pathological significance.