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HYBRIDOMAS SECRETING MONOCLONAL ANTIBODY TO TOXOPLASMA GONDII
Author(s) -
Johnson Alan M,
McNamara PJ,
Neoh SH,
McDonald PJ,
Zola H
Publication year - 1981
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1981.23
Subject(s) - subclass , monoclonal antibody , antibody , toxoplasma gondii , immunofluorescence , secretion , virology , direct fluorescent antibody , biology , indirect immunofluorescence , hemagglutination , immunology , microbiology and biotechnology , biochemistry
Summary Six hybridomas that secrete monoclonal antibody to Toxoplasma gondii have been developed. Four of these secrete antibody of the IgG1 subclass, one secretes antibody of the IgG2a subclass and the remaining hybridoma secretes antibody of the IgG3 subclass. One IgG1 subclass antibody reacts only in the indirect haemagglutination antibody test (IHAT), four (3 IgG1 and 1 IgG2a) react only in the indirect immunofluorescence antibody test (IFAT), and the IgG3 antibody reacts in both the IHAT and IFAT.