THE KINETIC BEHAVIOUR OF RADIOLABELLED IgG 1  DERIVED FROM DIFFERENT SOURCES IN ADULT SHEEP AND NEONATAL LAMBS | Zendy

Cripps AW | Zendy; Steel JW | Zendy; Lascelles AK | Zendy

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THE KINETIC BEHAVIOUR OF RADIOLABELLED IgG 1 DERIVED FROM DIFFERENT SOURCES IN ADULT SHEEP AND NEONATAL LAMBS

Author(s) -

Cripps AW,

Steel JW,

Lascelles AK

Publication year - 1979

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1979.15

Subject(s) - kinetic energy , zoology , chemistry , biology , physics , classical mechanics

Summary The turnover rate and pool volume of radiolabelled autologous IgG 1 was similar to homologous IgG 1 in adult sheep. In neonatal lambs there was no significant difference for either of these parameters between homologous serum IgG 1 and maternal colostrum IgG 1 . However, the pool volume for IgG 1 expanded by approx. 30% over the experimental period in the lambs. When the turnover rates were corrected for this increase they were found to be similar to those observed for IgG 1 in adult animals.

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