ENHANCEMENT OF NITROBLUE TETRAZOLIUM DYE REDUCTION BY LEUCOCYTES EXPOSED TO A FACTOR RELEASED FROM SENSITISED LYMPHOCYTES | Zendy

Oleske JM | Zendy; Ashman RB | Zendy; Kohl S | Zendy; Nahmias AJ | Zendy

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ENHANCEMENT OF NITROBLUE TETRAZOLIUM DYE REDUCTION BY LEUCOCYTES EXPOSED TO A FACTOR RELEASED FROM SENSITISED LYMPHOCYTES

Author(s) -

Oleske JM,

Ashman RB,

Kohl S,

Nahmias AJ

Publication year - 1979

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1979.11

Subject(s) - nitroblue tetrazolium , in vitro , immunology , formazan , antigen , chemistry , microbiology and biotechnology , biology , biochemistry

Summary Leucocytes from purified protein derivative (PPD) skin test positive individuals, after exposure to PPD in vitro . show a significant increase in nitroblue tetrazolium (NBT) dye reduction when compared to leucocytes from PPD negative donors. The active principle was shown to be soluble, and was released from lymphocytes after a rapid, immunologically specific interaction with the sensitising antigen.

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