RADIOIMMUNOASSAY OF SECRETIN IN SERUM | Zendy

Ho P | Zendy; Hansky J | Zendy

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RADIOIMMUNOASSAY OF SECRETIN IN SERUM

Author(s) -

Ho P,

Hansky J

Publication year - 1979

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1979.10

Subject(s) - secretin , radioimmunoassay , medicine , endocrinology , basal (medicine) , chemistry , microgram , pancreas , biochemistry , in vitro , insulin

Summary A radioimmnunoassay for the measurement of immunoreactive secretin has been developed. The assay is specific and sensitive so that 2·8 fmol/ml can be measured. Basal secretin levels inn man are generally undetectable and a protein‐rich meal does not elicit a secretin reponse. However, the intraduodenal instillation of HCl leads to a prompt rise in circulating immunoreactive secretin and exogenous secretin administered intravenously is easily and accurately measured.

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