Premium
ANTIBODY RESPONSES TO INFLUENZA VACCINES CONTAINING A/NEW JERSEY/8/76
Author(s) -
Feery BJ,
Hampson AW,
Rodda SJ,
Evered MG
Publication year - 1978
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1978.72
Subject(s) - antibody , virology , neuraminidase , immunization , antibody response , bivalent (engine) , vaccination , immunology , hemagglutination , virus , biology , chemistry , organic chemistry , metal
Summary Studies were undertaken with whole virus, subunit and adsorbed subunit influenza vaccines containing the A/New Jersey/8/76 strain to compare the antibody responses induced by immunization with these vaccines. There were no significant differences in the haemagglutination‐inhibition (HI) antibody responses to A/New Jersey/8/76 induced by these vaccines in the adult groups under study. Vaccinees over 23 years of age produced good HI antibody responses to one dose of vaccine. Neuraminidase antibody and complement‐fixing (CF) antibody responses were determined for the A/Victoria/3/75 component of bivalent vaccines. There were significant increases in neuraminidase inhibiting (NI) antibody titres but no increase in the complement‐fixing antibody titres after vaccination.