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EFFECTS OF A HYPERCALORIC HIGH CARBOHYDRATE DIET ON ADIPOSE TISSUE METABOLISM IN MAN
Author(s) -
Chinayon S,
Goldrick RB
Publication year - 1978
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1978.47
Subject(s) - lipolysis , adipose tissue , carbohydrate , medicine , endocrinology , carbohydrate metabolism , white adipose tissue , metabolism , chemistry , biology
Summary The effects of a hypercaloric high carbohydrate diet on lipolysis and esterification were studied in biopsy samples of adipose tissue obtained from 5 healthy subjects. Overfeeding with carbohydrate enhanced the rate of esterification of free fatty acids (FFA) without any alteration in the rate of lipolysis. The release of FFA from adipose tissue was inhibited. These observations indicate that the utilization of glucose and FFA by adipose tissue for the synthesis of triglycerides was facilitated during weight gain on a high carbohydrate diet.