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IN VITRO GROWTH OF OVINE SQUAMOUS CELL CARCINOMA
Author(s) -
Jun MH,
Johnson RH,
Maguire DJ,
Pratt MS
Publication year - 1978
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1978.41
Subject(s) - in vitro , biology , basal cell , cell , cell culture , ploidy , epithelium , carcinoma , pathology , microbiology and biotechnology , genetics , gene , medicine
Summary Cultured by fragment explantation following a selective trypsinisation procedure, 22/31 (71%) specimens of ovine squamous cell carcinoma yielded pure strains of epithelial cells which do date have passaged vigorously to the 29th level of passage. In contrast to the diploid nature of epithelial cell strains derived from foetal sheep skin, the cell strains derived from skin tumors were highly aneuploid.