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SUSCEPTIBILITY OF ORBIVIRUSES TO LOW pH AND TO ORGANIC SOLVENTS
Author(s) -
Gorman BM
Publication year - 1978
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1978.39
Subject(s) - chloroform , virus , acrylamide , virology , chemistry , electrophoresis , rna , polyacrylamide gel electrophoresis , biology , chromatography , microbiology and biotechnology , biochemistry , organic chemistry , enzyme , polymer , gene , copolymer
Summary Six orbiviruses, Corriparta, Wallal, Eubenangee, D'Aguilar, Warrego and Mitchell River, were inactivated within 30 min in solutions of pH less than 6. All but Wallal virus resisted treatment with ether at 1° for 22 h but only Corriparta virus resisted treatment with chloroform at 1° for 22 h. The genomes of the orbiviruses, including Corriparta virus, after electrophoresis in acrylamide gels separated into basically similar patterns which ware distinct from the pattern of reovirus RNA.