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THE ORIGIN AND SIGNIFICANCE OF MACROPHAGES IN THORACIC DUCT LYMPH
Author(s) -
Roser Bruce J
Publication year - 1976
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1976.55
Subject(s) - thoracic duct , lymph duct , lymph , lymphatic system , medicine , duct (anatomy) , pathology , efferent , population , lymphocyte , efferent ducts , anatomy , immunology , andrology , epididymis , afferent , sperm , environmental health
Summary Efferent lymph collected from a thoracic duct fistula initially contains no macrophages. However, the surgical procedures used to insert plastic cannulae into efferent lymphatics incite a vigorous foreign body reaction leading to the contamination of collected lymph with significant numbers of these cells. A sensitive and specific assay for the presence of macrophages in lymphocyte populations was used to quantitate the degree of contamination in rats bearing thoracic duct cannulae. The origin of some of these contaminant cells from the peritoneal macrophage population was established by adoptive transfer of labelled peritoneal cells to cannulated recipients.