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THE SPECIFICITY OF NEMATODE ALLERGENS IN THE DIAGNOSIS OF HUMAN VISCERAL LARVA MIGRANS
Author(s) -
HogarthScott RS,
Feery Brian J
Publication year - 1976
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1976.32
Subject(s) - toxocara canis , ascaris lumbricoides , visceral larva migrans , nematode , biology , ascaris , canis , larva , ascariasis , parasite hosting , larva migrans , helminthiasis , helminths , immunology , antigen , ecology , world wide web , computer science
Summary Extracts of nematodes have been used as skin test antigens in the diagnosis of nematode infections for many years. Ascaris lumbricoides and Taxocara canis are two nematodes commonly involved in human parasitism, the latter being associated with the clinical condition of Visceral Larva Migrans. In vitro and in vivo experiments reported in this paper confirm experimentally, as well as clinically, the existence of cross‐reacting antigens between T. canis and Ascaris spp., and probably between T. canis and other nematodes. These cross‐reactions compromise the usefulness of skin tests in the diagnosis of such parasitic infections.