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RELEASE OF GASTRIN BY VAGAL STIMULATION IN THE ACID SECRETORY RESPONSE TO FOOD
Author(s) -
Hunt DR,
Forrest APM
Publication year - 1976
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1976.18
Subject(s) - gastrin , sham feeding , medicine , antrum , stimulation , vagotomy , endocrinology , denervation , gastric acid , chemistry , stomach , secretion
Summary Gastric pouches were constructed in 8 dogs; in 4 they were of denervated type and in 4 the innervation was intact. An oesophageal fistula was then prepared in each dog. The acid secretory response to oral, tube and sham feeding was determined before and after denervation of the pyloric antrum. The results support the view that vagal release of gastrin makes a relatively small contribution to the total acid secretory response to food.