DIFFERENCES IN GENETIC SPECIFICITY ARE OBSERVED WHEN SPLEEN AND LYMPH NODE LEUCOCYTES ARE USED AS THE RESPONSIVE CELL POPULATION IN MIXED LEUCOCYTE CULTURES | Zendy

Lafferty KJ | Zendy; Ryan Madeleine A | Zendy

Premium

DIFFERENCES IN GENETIC SPECIFICITY ARE OBSERVED WHEN SPLEEN AND LYMPH NODE LEUCOCYTES ARE USED AS THE RESPONSIVE CELL POPULATION IN MIXED LEUCOCYTE CULTURES

Author(s) -

Lafferty KJ,

Ryan Madeleine A

Publication year - 1974

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1974.57

Subject(s) - spleen , lymph node , population , stimulation , biology , immunology , cell , microbiology and biotechnology , lymph node stromal cell , andrology , medicine , genetics , endocrinology , environmental health

Summary In mixed leucocyte culture, CBA lymph node cells respond to stimulation by irradiated (CBA x C57Bl) F 1 spleen cells, but (CBA x C57Bl) F 1 lymph node cells are not stimulated by irradiated CBA spleen cells. However, when spleen cells are the responsive cell population. (CBA x C57Bl) F 1 cells respond to stimulation by irradiated CBA spleen cells and CBA spleen cells respond to stimulation by irradiated (CBA x C57Bl) F 1 spleen cells.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research