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THE ROLE IN CHYLOMICRON FORMATION OF PHOSPHOLIPASE ACTIVITY OF INTESTINAL GOLGI MEMBRANES
Author(s) -
Redgrave TG
Publication year - 1973
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1973.41
Subject(s) - chylomicron , golgi apparatus , phospholipase , microbiology and biotechnology , phospholipase c , intracellular , biochemistry , chemistry , biology , cell , enzyme , cholesterol , very low density lipoprotein , lipoprotein
Summary The Golgi membrane which is associated with intracellular lipid droplets (“pre‐chylomicrons”) during intestinal absorption of fat has been shown to possess phospholipase A. phospholipase B and triglyceride lipase activities. These findings suggest that extrusion of chylomicrons from the intestinal cell might be accomplished by the action of phospholipases on Golgi and plasma membrane phospholipids Fusion of membranes could result from the localised action of phospholipase B, which, perhaps acting together with phospholipase A, would enable exteriorization of Golgi vacuoles and discharge of chylomicrons into the intercellular space.