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MACROPHAGE ACTIVATION IN MICE INFECTED WITH ECTROMELIA OR LYMPHOCYTIC CHORIOMENIGTIS VIRUSES
Author(s) -
Blanden RV,
Mims CA
Publication year - 1973
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1973.35
Subject(s) - lymphocytic choriomeningitis , ectromelia virus , listeria monocytogenes , spleen , peritoneum , virology , virus , ectromelia , biology , macrophage , rickettsia , arenavirus , microbiology and biotechnology , immunology , bacteria , immune system , in vitro , genetics , gene , cd8 , vaccinia , recombinant dna , biochemistry , anatomy
Summary Macropharge activation, as demonstrated by an increased ability to kill a bacterium ( Listeria monocytogenes ) occurred in virus‐infected mice the phenomenon was present in the liver, spleen and peritoneum eight days after infection with lymphocytic choriomeningitis virus and in the liver and peritoneum eight days after ectromelia virus infection. The mechanisms of macropossible significance in viral infection are discussed.