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BETA ADRENOCEPTORS IN THE RABBIT EAR ARTERY
Author(s) -
Carroll PR,
Glover WE
Publication year - 1973
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1973.30
Subject(s) - isoprenaline , propranolol , medicine , vasodilation , histamine , endocrinology , stimulation , chemistry
Summary Isoprenaline caused relaxation of isolated perfused ear arteries and arterial strips tonically contracted in response to potassium, histamine or nor‐adrenaline, and transient responses to injections of vasoconsrrictor drugs were reduced or abolished when isoprenaline was present in the perfusate or injected 5–10 seconds before the vasoconstrictor stimulus. The isoprenaline effect was abolished by propranolol, and it is concluded that beta‐receptors are present in this preparation and that their stimulation causes vasodilatation.