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THE PRESSOR EFFECT OF ANGIOTENSIN II IN PREGNANT SHEEP
Author(s) -
BlairWest JR,
Coghlan JP,
Denton DA,
Scoggins BA,
Wintour E Marelyn
Publication year - 1972
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1972.67
Subject(s) - sodium , angiotensin ii , endocrinology , renin–angiotensin system , medicine , pressor response , pregnancy , extracellular , extracellular fluid , gestation , intracellular , chemistry , blood pressure , biology , biochemistry , heart rate , organic chemistry , genetics
Summary The pressor response to intravenous angiotensin II was depressed in sheep during the last third of gestation in a manner similar to that observed in sodium depletion. Sodium deficiency during pregnancy did not further depress it. It is suggested that reduced extracellular or intracellular sodium concentration may be the modifying factor in both pregnancy and sodium deficiency.