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THE EFFECT OF MATERNAL MALNUTRITION ON THE PROGENY IN THE RAT:
Author(s) -
McLeod Katrine I,
Goldrick RB,
Whyte HM
Publication year - 1972
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1972.66
Subject(s) - creatinine , offspring , urea , malnutrition , urine , endocrinology , medicine , gestation , amino acid , protein malnutrition , biology , pregnancy , zoology , chemistry , biochemistry , genetics
Summary Female rats maintained on a protein‐deficient diet during gestation gave birth to stunted offspring. The progeny, raised on a well balanced diet, grew at a normal rate until the age of twelve to sixteen weeks when their rate of growth became abnormally slow. This slowing down of the rate of growth was associated with an excessive loss of urea, creatinine and α amino acid nitrogen in the urine. Plasma levels of urea, creatinine and α amino acid nitrogen were normal.