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SPECIES VARIATION IN GALACTOKINASE ACTIVITY OF ERYTHROCYTES, LENS AND LIVER
Author(s) -
Gupta JD,
Irvine Susan,
Harley JD
Publication year - 1972
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1972.43
Subject(s) - galactose , galactokinase , rabbit (cipher) , lens (geology) , galactosemia , biology , chemistry , biochemistry , endocrinology , medicine , paleontology , statistics , mathematics , escherichia coli , gene
Summary Methaemoglobin reduction by erythrocytes from mature humans, rabbits and rats was less rapid with galactose than with glucose as substrate. With galactose, rates of methaemoglobin reduction were approximately equal in human and rat, but considerably less than in rabbit erythrocytes. Galactokinase activity, on the other hand, was greater in rabbit and rat than in human erythrocytes, approximately the same in rabbit and rat erythrocytes, approximately the same in rabbit and rat liver but considerably less in rat than rabbit lens. It is suggested that the differences observed may at least in part determine variation between these species in susceptibility to galactose cataractogenicity.