Premium
EFFECTS OF PARATHYROID EXTRACT AND GLYCEROL ON 32 P UPTAKE IN RAT RENAL TISSUE
Author(s) -
Geary CP,
Cousins FB
Publication year - 1971
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1971.50
Subject(s) - glycerol , chemistry , parathyroid hormone , in vivo , medicine , endocrinology , kidney , phosphorus , biochemistry , calcium , biology , microbiology and biotechnology , organic chemistry
Summary Parathyroid extract enhanced cellular turnover of 32 P in rat kidney in vivo and in vitro . The parathyroid extract contained glycerol, and injected glycerol alone increased the uptake of 32 P by renal tissue as much as 50%. Glycerol, but not parathyroid extract, also increased the renal content of phosphorus. Parathyroid extract, a glycerol‐free parathyroid extract, and glycerol all stimulated the uptake of 32 P in rat renal cortical slices under aerobic conditions, glycerol having the greatest effect. Separation of phosphate fractions suggested that glycerol and parathyroid extract stimulated the uptake of 32 P by different pathways.