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TRANSFER OF GENES RELATED TO UNRESPONSIVENESS TO BOVINE SERUM ALBUMIN FROM SOBEY TO BALB/C MICE
Author(s) -
Hardy D,
Kotlarski Ieva
Publication year - 1971
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1971.39
Subject(s) - bovine serum albumin , balb/c , outbreeding depression , serum albumin , albumin , biology , antibody , gene , immunology , microbiology and biotechnology , endocrinology , biochemistry , medicine , immune system , inbreeding , population , environmental health
Summary Unsatisfactory breeding of Sobey mice (genetically unresponsive to bovine serum albumin) has necessitated an outbreeding programme to transfer the genes related to unresponsiveness from Sobey to BALB/c mice. Responses to bovine serum albumin of mice at various stages in the breeding programme are given. A more sensitive method of assaying anti‐bovine serum albumin antibodies has been used to select low responding mice.