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ULTRASTRUCTURAL CHANGES CAUSED BY SWAINSCWA GALEGIFOLIA POISONING IN THE GUINEA‐PIG
Author(s) -
Huxtable CR
Publication year - 1970
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1970.7
Subject(s) - ultrastructure , guinea pig , vacuole , organelle , electron microscope , biology , microbiology and biotechnology , chemistry , pathology , cytoplasm , anatomy , endocrinology , medicine , physics , optics
Summary Vacuolation of the cells of many tissues has been produced by feeding guinea‐pigs on Swainsona galegifolia. Medullary neurones, hepatocytes, hepatic sinusoidal cells and pancreatic acinar cells from such animals have been examined with the electron microscope. In each case the vacuoles have been found to be single membrane‐bound and to have no clear‐cut morphological relationship with the normal organelles. Their possible relationship with lysosomes is discussed.