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STUDIES ON THE PLASMA PROTEIN BINDING OF [ 58 Co]‐VITAMIN B 12
Author(s) -
Beal RW,
Read Wendy MF
Publication year - 1969
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1969.43
Subject(s) - vitamin , chemistry , vitamin d binding protein , vitamin b , glycoprotein , chromatography , plasma protein binding , fraction (chemistry) , affinity chromatography , biochemistry , enzyme
Summary The vitamin B 12 binding capacity of separated plasma protein fractions has been measured at levels ranging from 10–100 ng./ml. of added radioactive vitamin B 12 . An α 1 acid glycoprotein has shown much greater vitamin B 12 binding properties than all other proteins tested; this protein has the same column chromatographic mobility as that protein fraction which binds abnormally large amounts of vitamin B 12 in chronic myeloid leukaemia.
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