Premium
TISSUE CATECHOLAMINE LEVELS IN NORMOTENSIVE, GENETICALLY HYPERTENSIVE AND RENAL HYPERTENSIVE RATS
Author(s) -
Robertson Allison A,
Hodge JV,
Laverty R,
Smirk FH
Publication year - 1968
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1968.175
Subject(s) - catecholamine , medicine , endocrinology , forebrain , caudate nucleus , kidney , renal artery , central nervous system
Summary Rats with genetic hypertension have been shown to have raised catecholamine levels in the forebrain, cerebellum and caudate nucleus when compared with control rats. In rats made hypertensive by renal artery narrowing, brain catecholamine levels were normal. Both hypertensive groups showed decreased concentrations of noradrenaline in heart muscle. Possible explanations of these changes are discussed.