HUMAN SERUM ALKALINE PHOSPHATASE VARIANTS AND THEIR ASSOCIATION WITH THE ABO BLOOD GROUPS IN AN AUSTRALIAN SAMPLE | Zendy

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HUMAN SERUM ALKALINE PHOSPHATASE VARIANTS AND THEIR ASSOCIATION WITH THE ABO BLOOD GROUPS IN AN AUSTRALIAN SAMPLE

Author(s) -

Hope RM

Publication year - 1966

Publication title -

australian journal of experimental biology and medical science

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.999

H-Index - 104

eISSN - 1440-1711

pISSN - 0004-945X

DOI - 10.1038/icb.1966.31

Subject(s) - abo blood group system , alkaline phosphatase , group a , biology , medicine , immunology , enzyme , biochemistry

Summary Starch gel electrophoresis of serum samples from 303 healthy adult Australians of known ABO blood group revealed 2 major zones of alkaline phosphatase activity. As reported by other workers, the staining intensity of the slower‐moving B zone varied between individuals, and this was associated with the ABO blood group of the donor. The majority of sera from group A donors showed little or no B zone activity, whereas sera from individuals of other ABO groups showed a wide range of B zone activity. Spectrophoto‐metric studies showed that the mean serum alkaline phosphatase activity of group B and O individuals was 18% higher than that of group A, group AB being intermediate in activity.

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