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MUTANTS RESISTANT TO COLICIN CA42‐E 2 : CROSS RESISTANCE AND GENETIC MAPPING OF A SPECIAL CLASS OF MUTANTS
Author(s) -
Reeves Peter
Publication year - 1966
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1966.29
Subject(s) - colicin , mutant , locus (genetics) , genetics , biology , escherichia coli , microbiology and biotechnology , gene
Summary Spontaneous mutants resistant to colicins CA42‐E 2 , or K317‐E 2 were isolated. Ninety‐five per cent of these mutants probably lack receptor; 10 of the remaining 5%, still possessing receptor and able to adsorb colicin, were studied further. They showed frequent cross resistance to 3 colicins of other types, CA31‐A, CA57‐C and K235‐K, yet were often sensitive to some other colicins of type E. Eight of these mutations were closely linked to Gal and are thought to be at a locus concerned with the bacterial system affected by the colicins involved.