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THE DISTRIBUTION OF GENETIC FACTORS IN MALARIA ANTIBODIES AS DETERMINED BY A FLUORESCENT ANTIBODY TEST
Author(s) -
Curtain CC,
Baumgarten A
Publication year - 1965
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1965.68
Subject(s) - malaria , antibody , biology , virology , gamma globulin , immunology
Summary The malaria antibody of 5 out of 34 Melanesian Gm (a + b + ) donors was found to possess no Gm (a + ) or Gm (b + ) specificity. In three others the malaria antibody possessed Gm (a + ) specificity only and in 1 Gm (b + ) specificity only. Eighteen of the 34 donors were Inv (a + ) and the malaria antibody possessed no Inv (a + ) specificity. It was suggested that phenotypic restriction of the malaria antibody might occur if the individual's initial experience of malaria in infancy occurred before all of the gamma globulin allotypes had developed.