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RELATED ANTIGENS IN MYCOPLASMA PNEUMONIAE AND MYCOPLASMA MYCOIDES VAR. MYCODES
Author(s) -
Lemcke Ruth M,
Shaw Elizabeth J,
Marmion BP
Publication year - 1965
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1965.61
Subject(s) - mycoplasma mycoides , microbiology and biotechnology , complement fixation test , mycoplasma pneumoniae , antiserum , biology , antigen , virology , serology , hemagglutination , mycoplasma , contagious bovine pleuropneumonia , antibody , pneumonia , virus , immunology , medicine
Summary Serological cross‐reactions have been observed between Mycoplasma pneumoniae and Mycoplasma mycoides in tests with convalescent‐phase sera From human begins with atypical pneumonia, with sera from rabbits hyper‐immunised with one or other of the two strains, and with post‐infection sera from cattle experimentally inoculated with M. mycoides . The cross‐reactions were most pronounced in complement‐fixation tests, less by immunofluorescence und least by growth inhibition. An ethanol extract (Dafaalla B fraction) and a semi‐purified polysaceharide (galactan) from M. mycoides reacted in gel‐diffusion and haemagglutination with antisera to M. pneumoniae . It is possible, therefore, that more than one antigenic component may be shared between the two mycoplasmas.