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THE ADSORPTION AND KINETICS OF KILLING BY COLICIN CA42‐E 2
Author(s) -
Reeves P
Publication year - 1965
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1965.18
Subject(s) - colicin , kinetics , adsorption , bacteria , chemistry , microbiology and biotechnology , molecule , biology , biochemistry , escherichia coli , genetics , physics , organic chemistry , quantum mechanics , gene
Summary The kinetics of the initial step of killing of sensitive bacteria by colicin CA42‐E 2 suggest that only one lethal unit or molecule is required to kill. Using a new sensitive assay it is shown that 30‐90 such lethal units can be adsorbed on one cell. Each lethal unit corresponds to 10 5 Dalton in the purified colicin which is similar to the probable molecular weight. The significance of these findings is discussed.