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OBSERVATIONS ON NZB/B1 MICE
Author(s) -
Bielschowsky Marianne,
Bielschowsky F
Publication year - 1964
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1964.52
Subject(s) - offspring , biology , fertility , genetics , demography , pregnancy , population , sociology
Summary In reciprocal crosses a deficit in numbers of offspring was noted when the male belonged to the NZB/B1 and the females to the NZO/B1 and NZY/B1 strains. In such matings the number of implantation sites was low. Only a small reduction in fertility was noted when NZC/B1 females were mated to NZB/B1 males. In offspring of reciprocal crosses NZB/B1 × NZC/B1 the incidence of autoimmune haemolytic anaemia was virtually 100 per cent in F 1 and 74 per cent in F 2 mice independent of sex of the NZB/B1 parent.