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PULMONARY DAMAGE DUE TO HIGH PRESSURE OXYGEN BREATHING IN RATS
Author(s) -
Jamieson Dana,
Brenk HAS
Publication year - 1964
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1964.45
Subject(s) - oxygen , lung , oxygen tension , surface tension , pentobarbital , compression (physics) , sodium , breathing , chemistry , tension (geology) , anesthesia , materials science , medicine , biophysics , composite material , biology , organic chemistry , physics , quantum mechanics
Summary The surface tension of films formed from lung extracts and the changes in surface tension on compression of such films have been studied in control rats respiring air and in rats exposed to oxygen at 5 atmospheres pressure (OHP). The surface tension recorded in films from oxygen poisoned lungs was higher at all areas of the film. Pentobarbital sodium, which protects rats against OHP‐induced lung damage, also caused some protection of the lung surface‐active material.