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THE APPLICATION OF THE FLUORESCENT ANTIBODY TECHNIQUE TO THE DETECTION OF CANDIDA ALBICANS IN ORAL PATHOLOGICAL MATERIAL
Author(s) -
Schamschula RG
Publication year - 1964
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1964.18
Subject(s) - candida albicans , serology , microbiology and biotechnology , antibody , fluorescence , organism , corpus albicans , biology , pathological , pathology , medicine , immunology , optics , physics , paleontology
Summary The fluorescent antibody technique was applied to the detection of Candida albicans in oral smears. C. albicans was identified by cultural methods in 44 of 50 cases of suspected Candidiasis. When the fluorescent antibody technique was used, the organism was detected and identified in the original pathological material in 42 cases (95·4 per cent). This technique appears to be superior to other commonly‐used microscopical methods as far as the facility of detection of the organism is concerned and has the added advantage of serological specificity.