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THROMBUS FORMATION IN VITRO : A RHEOLOGICAL AND MORPHOLOGICAL STUDY
Author(s) -
Rozenberg MC,
Dintenfass Leopold
Publication year - 1964
Publication title -
australian journal of experimental biology and medical science
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.999
H-Index - 104
eISSN - 1440-1711
pISSN - 0004-945X
DOI - 10.1038/icb.1964.13
Subject(s) - coagulation , rheology , thrombus , shear rate , viscometer , materials science , scanning electron microscope , platelet , platelet aggregation , in vivo , thrombosis , shear stress , shear (geology) , electron microscope , biophysics , chemistry , composite material , cardiology , medicine , optics , biology , viscosity , physics , microbiology and biotechnology
Summary Blond coagulation has been studied by means of viscometric techniques. Clots obtained have been examined with the light‐ and the electron‐microscope. The degree of platelet aggregation in these clots has been found to be a function of the rate of shear produced in the cone‐in‐conc viscometer. At high rates of shear, morphology obtained resembles that of in vivo thrombosis. The process of blood coagulation was found to be accelerated at higher velocity gradients.